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At
the 10th World Congress on Osteoarthritis in Boston Steven A. Mazzuca, Ph.D.
said earlier
: Lower-extremity
strength training may help to slow down the progression of
knee osteoarthritis symptoms in older individuals than
do conventional range-of-motion exercises.
Several previous studies have linked quadriceps
weakness with osteoarthritis, suggesting that weak leg
muscles may be a risk factor for the incidence of the
condition, said Dr. Mazzuca of the division of
rheumatology at Indiana University in Indianapolis.
“research has not clearly shown whether exercises
designed to improve leg strength can slow the
progression of osteoarthritis.”
Dr. Mazzuca and colleagues randomized a population-based
sample of 221 subjects (mean age 69 years) into either a
resistance-based strength-training intervention or a
range-of-motion intervention. In both groups, subjects
exercised three times per week for 12 weeks at a fitness
facility, then transitioned to home-based exercise by
month 12 and twice-yearly “booster” sessions until month
30. Attendance at scheduled exercise sessions was
similar between both groups. Of the original 221
subjects, 154 completed the study, including 72 from the
strength-training group and 82 from the range-of-motion
group, Dr. Mazzuca said.
At 30 months, those individuals randomized to quadriceps
strength training retained more strength than did those
in the range-of-motion group, and exhibited marginally
less frequent progressive joint-space narrowing, said
Dr. Mazzuca.
“Strength training decreased the rate of joint-space
narrowing by 26%” compared with range-of-motion
subjects, he said.
In addition, the percentage of osteoarthritic knees
exhibiting more than 0.50-mm joint-space narrowing was
marginally smaller in the strength-training group than
it was in the range-of-motion group.
However, among knees that were normal at baseline in the
strength-training group, the investigators observed an
increase in incident joint-space narrowing greater than
0.50 mm, compared with the range-of-motion group. This
was a finding that could not be explained, said Dr.
Mazzuca. This study
supports that lower extremities strength training may
help to prevent surgeries and
total knee replacement
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