Eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a newly recognized chronic disease that can be associated with food allergies. It is increasingly being diagnosed in children and adults. EoE is characterized by inflammation and accumulation of a specific type of immune cell, called an eosinophil, in the esophagus. Eosinophils are a type of white blood cell. They help fight off infections and play a role in your body’s immune response. They can also build up and cause inflammation. Normally your blood doesn’t have a large number of eosinophils. Your body may produce more of them in response to, allergic disorders, skin conditions, parasitic and fungal infection, autoimmune diseases, some cancers, and bone marrow disorders. In some conditions, the eosinophils can move outside the bloodstream and build up in organs and tissues. Symptoms of EoE include nausea, vomiting, and abdominal pain after eating. A person may also have symptoms that resemble acid reflux from the stomach. In older children and adults, it can cause more severe symptoms, such as difficulty swallowing solid food or solid food sticking in the esophagus for more than a few minutes. In infants, this disease may be associated with failure to thrive. In some situations, avoiding certain food allergens will be an effective treatment for EoE.

Disease Information