Mooren’s ulcer is a rare disease that studies suggest is an autoimmune disorder. Some cases run a chronic severe course and fail to respond to local and systemic therapy. Mooren’s ulcer is an idiopathic (unknown origin) noninfectious ulceration (The process or fact of being eroded away, as by an ulcer) of the peripheral cornea that has been classified into 2 clinical types. One is a milder, unilateral, less progressive form of the disease generally seen in elderly patients that responds well to therapy. The second type is a much more aggressive, frequently bilateral, relentless disease usually seen in younger patients that is poorly responsive to any therapy and often leads to corneal destruction.